Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.32 |
| ▸ | GHSR | Q92847 | 5/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27323725 | 1.00 | KCNH2 (0.36) | KCNH2CCR2SIGMAR1CYP2D6GHSR | |
| SCHEMBL27323721 | 1.00 | KCNH2 (0.36) | KCNH2CCR2SIGMAR1CYP2D6GHSR | |
| SCHEMBL27425331 | 0.91 | HRH3 (0.34) | SIGMAR1 | |
| SCHEMBL17827393 | 0.82 | KCNH2 (0.37) | KCNH2CCR2CYP2D6GHSRKAT2B | |
| SCHEMBL26949296 | 0.82 | KCNH2 (0.37) | KCNH2CCR2CYP2D6GHSRKAT2B | |
| SCHEMBL27323802 | 0.82 | KCNH2 (0.37) | KCNH2CCR2CYP2D6GHSRKAT2B | |
| SCHEMBL4384507 | 0.80 | KCNH2 (0.38) | KCNH2CCR2CYP2D6GHSRKAT2B | |
| SCHEMBL20224759 | 0.80 | KCNH2 (0.35) | KCNH2CCR2CYP2D6GHSRKAT2B | |
| SCHEMBL20942482 | 0.80 | KCNH2 (0.35) | KCNH2CCR2CYP2D6GHSRDRD2 | |
| SCHEMBL17702046 | 0.80 | HRH3 (0.42) | KCNH2SIGMAR1CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244918-A1 | QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-12-21 | — | — | WO | disclosed |