Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.83 |
| ▸ | LMNA | P02545 | 1/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PNMT | P11086 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2-Dichlorobenzene SCHEMBL27321264 | 0.96 | TSHR (0.77) | TSHRLMNAALDH1A1PNMTCYP2A6 | |
| 1,2-Dichlorobenzene SCHEMBL1155123 | 0.91 | TSHR (1.00) | TSHRLMNAALDH1A1PNMTCYP2A6 | |
| 1,2-Dichlorobenzene SCHEMBL29350623 | 0.91 | — | — | |
| 1,2-Dichlorobenzene SCHEMBL5190 | 0.91 | — | — | |
| 1,2-Dichlorobenzene SCHEMBL10593125 | 0.91 | — | — | |
| 1,2-Dichlorobenzene SCHEMBL8673472 | 0.87 | TSHR (0.91) | TSHRLMNAALDH1A1PNMTCYP2A6 | |
| 1,2-Dichlorobenzene SCHEMBL16793414 | 0.87 | — | — | |
| 1,2-Dichlorobenzene SCHEMBL11889383 | 0.87 | TSHR (0.91) | TSHRLMNAALDH1A1PNMTCYP2A6 | |
| 1,2-Dichlorobenzene SCHEMBL15353390 | 0.87 | — | — | |
| 1,2-Dichlorobenzene SCHEMBL2512630 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107674028-A | A kind of synthetic method of pyrazoline ketone compounds | 天津瑞岭化工有限公司 | 2018-02-09 | — | — | CN | claimed |
| CN-107652237-A | A kind of synthetic method of pyrazolone and its derivative | 天津瑞岭化工有限公司 | 2018-02-02 | — | — | CN | claimed |
| CN-102206182-B | Method for synthesizing Rimonabant hydrochloride | UNIV CHINA PHARMA | 2013-03-13 | — | — | CN | claimed |
| CN-101585810-B | Preparation method of 5-(4-chlorphenyl)-1-(2, 4-dichlorophenyl) 4- methylpyrazole-3-formic ether | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2011-12-14 | — | — | CN | claimed |
| CN-102206182-A | Method for synthesizing Rimonabant hydrochloride | UNIV CHINA PHARMA | 2011-10-05 | — | — | CN | claimed |
| CN-101456843-B | Synthesis method of 5- (4-chlorphenyl) -1- (2, 4-dichlorophenyl) -4-methylpyrazole-3-carboxylic acid | NANJING UNIVERSITY OF TECHNOLOGY | 2011-01-19 | — | — | CN | claimed |
| CN-101585810-A | Preparation method of 5-(4-chlorphenyl)-1-(2, 4-dichlorophenyl) 4- methylpyrazole-3-formic ether | UNIV EAST CHINA SCIENCE & TECH (CN) | 2009-11-25 | — | — | CN | claimed |
| CN-101456843-A | Synthesis method of 5- (4-chlorphenyl) -1- (2, 4-dichlorophenyl) -4-methylpyrazole-3-carboxylic acid | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2009-06-17 | — | — | CN | claimed |
| CN-101314591-A | Novel pyrazoles highly-selective marijuana acceptor-1antagon and/or reversed activation agent | SHANGHAI SUN SAIL PHARMACEUTIC (CN) | 2008-12-03 | — | — | CN | claimed |
| CN-117486801-A | Synthesis process for continuously preparing Ai Qubo Pa by using 3D printing forming technology | 南京恒通医药开发有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-105209030-B | For stablizing the compound that blue Buddhist nun's alkali receptor makes it from the calcium release of abnormal level | 罗莎琳德富兰克林医科大学 | 2018-06-12 | — | — | CN | disclosed |
| CN-107946644-A | A kind of environmental protection lithium battery electrolytes | 杨彬 | 2018-04-20 | — | — | CN | disclosed |
| CN-107915677-A | The preparation method of eltrombopag olamine | 孙婷婷 | 2018-04-17 | — | — | CN | disclosed |
| CN-107033021-A | A kind of preparation method of 2,4 dichloro phenyl hydrazine | 重庆锦杉科技有限公司 | 2017-08-11 | — | — | CN | disclosed |
| CN-1328559-A | CRF receptor antagonists and methods relating thereto | NEUROCRINE BIOSCIENCES INC (US) | 2001-12-26 | — | — | CN | disclosed |
| CN-1070185-C | Preparation method of N-substituted 3-hydroxypyrazole compound | BASF AG (DE) | 2001-08-29 | — | — | CN | disclosed |
| CN-1190961-A | Process for producing N-substituted 3-hydroxypyrazoles | BASF AG (DE) | 1998-08-19 | — | — | CN | disclosed |
| CN-1142492-A | Substituted N-(indole-2-carbonyl)-glycinamides and derivatives as antidiabetic agents | PFIZER (US) | 1997-02-12 | — | — | CN | disclosed |
| CN-1110968-A | Substituted N-piperidino-pyrazole-3-carboxamide | SANOFI SA (FR) | 1995-11-01 | — | — | CN | disclosed |
| CN-1044576-A | With 1,8-naphthoic acid acid anhydride cover crop is to resist the damage of triazolinone herbicide | FMC CORP (US) | 1990-08-15 | — | — | CN | disclosed |