SCHEMBL27324488

SCHEMBL27324488

C=C(Cl)CON[C]=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9034343 0.76
SCHEMBL515513 0.67
SCHEMBL8012547 0.66
SCHEMBL8000387 0.66
SCHEMBL21198886 0.62
SCHEMBL5649238 0.62
SCHEMBL8078648 0.60
SCHEMBL14331819 0.60 MGAM (0.42)
SCHEMBL21198889 0.60
SCHEMBL8016161 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1289498-C 1-methylcarbapenem derivatives SANKYO CO (JP) 2006-12-13 CN disclosed
CN-1486317-A 1-methylcarbapenem derivatives ������������ʽ���� 2004-03-31 CN disclosed
CN-1048494-C Process for preparing carbapenen and penem compounds and new compounds involved in that process SANKYO CO (JP) 2000-01-19 CN disclosed
CN-1034498-C Octahydronaphthalene oxime derivatives for cholesterol biosynthesis inhibition, their preparation and use SANKYO CO (JP) 1997-04-09 CN disclosed
CN-1094728-A Prepare the method for carbapeneme and penem and the new compound that relates to SANKYO CO (JP) 1994-11-09 CN disclosed
CN-1084162-A Be used to suppress the biosynthetic octahydronaphthalene oxime derivative of cholesterol, Preparation Method And The Use SANKYO CO (JP) 1994-03-23 CN disclosed