SCHEMBL27324935

SCHEMBL27324935

C[C@@H](C#N)CNc1cc(-c2cnccc2-c2nncn2C)cc(N2Cc3c(cc(CN4CCC5(CC5)C4)cc3C(F)(F)F)C2=O)n1

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27297280 1.00 CBLB (0.48) CBLB
SCHEMBL27297158 1.00 CBLB (0.48) CBLB
SCHEMBL27299597 0.94 CBLB (0.47) CBLB
SCHEMBL27299557 0.94 CBLB (0.47) CBLB
SCHEMBL30956945 0.94 CBLB (0.47) CBLB
SCHEMBL30956941 0.94 CBLB (0.47) CBLB
SCHEMBL27299556 0.94 CBLB (0.47) CBLB
SCHEMBL27295791 0.94 CBLB (0.51) CBLB
SCHEMBL27298039 0.93 CBLB (0.51) CBLB
SCHEMBL27298140 0.93 CBLB (0.51) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024081311-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2024-04-18 — — WO disclosed
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