Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 15/20 | 0.42 |
| ▸ | NPY1R | P25929 | 9/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.42 |
| ▸ | NPY2R | P49146 | 5/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14199862 | 0.88 | NPY4R (0.40) | NPY4RNPY1RNPY5RNPY2RITGB3 | |
| SCHEMBL11950325 | 0.84 | NPY4R (0.36) | NPY4RNPY1RNPY5RNPY2RALOX15 | |
| SCHEMBL16383647 | 0.84 | NPY4R (0.36) | NPY4RNPY1RNPY5RNPY2RALOX15 | |
| SCHEMBL12837508 | 0.81 | NPY4R (0.39) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL27484587 | 0.81 | MEN1 (0.40) | NPY4RNPY1RNPY5RNPY2RITGB3 | |
| SCHEMBL27484588 | 0.81 | MEN1 (0.40) | NPY4RNPY1RNPY5RNPY2RITGB3 | |
| SCHEMBL24157931 | 0.81 | NPY4R (0.40) | NPY4RNPY1RNPY5RNPY2RALOX15 | |
| SCHEMBL11950333 | 0.81 | NPY4R (0.38) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL8227032 | 0.81 | NPY4R (0.38) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL14028975 | 0.81 | NPY4R (0.38) | NPY4RNPY1RNPY5RNPY2RKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024103400-A1 | POLYCYCLIC COMPOUND AS GPR75 ACTIVATOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 水木未来(北京)科技有限公司 | 2024-05-23 | — | — | WO | disclosed |