Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NRAS | P01111 | 5/20 | 0.36 |
| ▸ | FLT3 | P36888 | 5/20 | 0.36 |
| ▸ | FYN | P06241 | 2/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | CDK7 | P50613 | 1/20 | 0.30 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.30 |
| ▸ | CCNH | P51946 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31739697 | 1.00 | NRAS (0.36) | NRASFLT3FYNLCKRET | |
| SCHEMBL27329389 | 1.00 | NRAS (0.36) | NRASFLT3FYNLCKRET | |
| SCHEMBL27330018 | 0.93 | FLT3 (0.40) | NRASFLT3FYNLCKRET | |
| SCHEMBL27327395 | 0.93 | FLT3 (0.40) | NRASFLT3FYNLCKRET | |
| SCHEMBL27198235 | 0.91 | NRAS (0.45) | NRASFLT3FYNLCKRET | |
| SCHEMBL27331195 | 0.91 | NRAS (0.45) | NRASFLT3FYNLCKRET | |
| SCHEMBL27326933 | 0.89 | FLT3 (0.41) | NRASFLT3FYNLCKRET | |
| SCHEMBL27329396 | 0.89 | FLT3 (0.41) | NRASFLT3FYNLCKRET | |
| SCHEMBL31739830 | 0.88 | FLT3 (0.41) | NRASFLT3FYNLCKRET | |
| SCHEMBL27326930 | 0.88 | FLT3 (0.41) | NRASFLT3FYNLCKRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023245123-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2023-12-21 | — | — | WO | disclosed |