Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 17/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | KDM1A | O60341 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9294551 | 1.00 | TACR1 (0.69) | TACR1CYP2D6KDM1AMAOAMAOB | |
| SCHEMBL27316872 | 0.89 | TACR1 (0.67) | TACR1CYP2D6KCNH2 | |
| SCHEMBL9294294 | 0.81 | TACR1 (0.67) | TACR1CYP2D6KDM1AMAOAMAOB | |
| Cp-99994 SCHEMBL1282327 | 0.81 | TACR1 (1.00) | TACR1CYP2D6KCNH2 | |
| SCHEMBL9294299 | 0.81 | TACR1 (0.67) | TACR1CYP2D6KDM1AMAOAMAOB | |
| Cp-99994 SCHEMBL14513344 | 0.81 | TACR1 (1.00) | TACR1CYP2D6KCNH2 | |
| Cp-99994 SCHEMBL3951615 | 0.81 | TACR1 (1.00) | TACR1CYP2D6KCNH2 | |
| Cp-99994 SCHEMBL29375350 | 0.81 | TACR1 (1.00) | TACR1CYP2D6KCNH2 | |
| Cp-99994 SCHEMBL9295413 | 0.81 | TACR1 (1.00) | TACR1CYP2D6KCNH2 | |
| Cp-99994 SCHEMBL6827944 | 0.81 | TACR1 (1.00) | TACR1CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1045595-C | Process for the preparation of the intermediates used in the synthesis of 3-aminopiperidine derivatives | PFIZER (US) | 1999-10-13 | — | — | CN | disclosed |
| CN-1035944-C | 3-aminopiperidine derivatives and related nitrogen-containing heterocyclic compounds | PFIZER (US) | 1997-09-24 | — | — | CN | disclosed |
| CN-1087083-A | The intermediates preparation of synthetic 3-amino piperidine derivatives | PFIZER (US) | 1994-05-25 | — | — | CN | disclosed |
| CN-1053060-A | 3-aminopiperidine derivatives and related nitrogen-containing heterocycles | PFIZER (US) | 1991-07-17 | — | — | CN | disclosed |