Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | G6PD | P11413 | 1/20 | 0.49 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27331759 | 0.90 | S1PR4 (0.47) | MAPTKDM4ES1PR4S1PR2S1PR1 | |
| SCHEMBL27327251 | 0.83 | MAPT (0.45) | POLBG6PDTP53MAPTBLM | |
| SCHEMBL27331754 | 0.83 | HSD17B2 (0.46) | POLBMAPTKDM4ES1PR4GAA | |
| SCHEMBL1797569 | 0.77 | SERPINE1 (0.56) | POLBG6PDSERPINE1TP53MAPT | |
| SCHEMBL27327254 | 0.76 | MAPT (0.54) | POLBG6PDTP53MAPTBLM | |
| SCHEMBL27331752 | 0.76 | KDM4E (0.51) | MAPTKDM4ES1PR4S1PR2S1PR1 | |
| SCHEMBL27327673 | 0.75 | HSD17B2 (0.50) | TP53MAPTBLMKDM4EHSD17B10 | |
| SCHEMBL27331373 | 0.74 | HSD17B2 (0.43) | POLBMAPTKDM4ES1PR4GAA | |
| SCHEMBL27327253 | 0.72 | S1PR4 (0.45) | S1PR4S1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL1796212 | 0.71 | TP53 (0.69) | POLBSERPINE1TP53MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024103400-A1 | POLYCYCLIC COMPOUND AS GPR75 ACTIVATOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 水木未来(北京)科技有限公司 | 2024-05-23 | — | — | WO | disclosed |