Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 11/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27331226 | 0.91 | MAPT (0.49) | S1PR4S1PR5TP53MAPTBLM | |
| SCHEMBL27327438 | 0.91 | S1PR4 (0.46) | S1PR4S1PR5TP53MAPTBLM | |
| SCHEMBL27327433 | 0.90 | S1PR4 (0.47) | S1PR4S1PR5TP53MAPTBLM | |
| SCHEMBL27327436 | 0.90 | S1PR4 (0.47) | S1PR4S1PR5TP53MAPTBLM | |
| SCHEMBL27327444 | 0.87 | S1PR4 (0.42) | S1PR4S1PR5TP53MAPTBLM | |
| SCHEMBL27327446 | 0.85 | S1PR4 (0.40) | S1PR4S1PR5TP53MAPTBLM | |
| SCHEMBL27331219 | 0.81 | MAPT (0.51) | S1PR4S1PR5TP53MAPTBLM | |
| SCHEMBL27329641 | 0.81 | MAPT (0.49) | S1PR4S1PR5TP53MAPTBLM | |
| SCHEMBL27331222 | 0.81 | MAPT (0.51) | S1PR4S1PR5TP53MAPTBLM | |
| SCHEMBL27327257 | 0.81 | S1PR4 (0.48) | S1PR4S1PR5TP53MAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024103400-A1 | POLYCYCLIC COMPOUND AS GPR75 ACTIVATOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 水木未来(北京)科技有限公司 | 2024-05-23 | — | — | WO | disclosed |