SCHEMBL27329281

SCHEMBL27329281

CCOC(=O)CC(C(=O)OCC)S(=O)(=O)O.[NaH].[NaH]

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.51
GAA P10253 2/20 0.43
MGAM O43451 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
ALDH1A1 P00352 6/20 0.41
ALOX15 P16050 3/20 0.41
CYP3A4 P08684 2/20 0.41
TSHR P16473 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
HSD17B10 Q99714 2/20 0.40
CHRM1 P11229 1/20 0.40
ADORA1 P30542 1/20 0.40
TRPA1 O75762 1/20 0.40
CYP2D6 P10635 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP1A2 P05177 1/20 0.35
KMT2A Q03164 3/20 0.35
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL662228 1.00 RECQL (0.51) RECQLGAAMGAMSIMGAM2
SCHEMBL342416 0.98 RECQL (0.53) RECQLGAAMGAMSIMGAM2
SCHEMBL5702216 0.96 RECQL (0.51) RECQLGAAMGAMSIMGAM2
SCHEMBL5702076 0.96 RECQL (0.51) RECQLGAAMGAMSIMGAM2
SCHEMBL9533564 0.89 RECQL (0.45) RECQLGAAMGAMSIMGAM2
SCHEMBL3092985 0.89 RECQL (0.45) RECQLGAAMGAMSIMGAM2
SCHEMBL14619503 0.86 RECQL (0.46) RECQLGAAMGAMSIMGAM2
SCHEMBL3857717 0.86 RECQL (0.46) RECQLGAAMGAMSIMGAM2
SCHEMBL18312938 0.86 GAA (0.46) RECQLGAAMGAMSIMGAM2
SCHEMBL17925316 0.86 RECQL (0.44) RECQLGAAMGAMSIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105461909-A Sulfopolyester polymer compositions with improved water dispersibility EASTMAN CHEM CO 2016-04-06 CN disclosed
CN-102276732-B Cellulose interpolymers and method for oxidation EASTMAN CHEM CO. (US) 2016-01-20 CN disclosed
CN-102439095-B Refinish coating compositions comprising low molecular weight cellulose mixed esters EASTMAN CHEMICAL CO. (US) 2014-10-08 CN disclosed
CN-102307960-B Coating compositions containing acrylic and aliphatic polyester blends EASTMAN CHEM CO 2014-08-06 CN disclosed
CN-103649170-A Sulfopolyester polymer compositions with improved water dispersibility EASTMAN CHEM CO 2014-03-19 CN disclosed
CN-101528875-B Low-VOC additives to extend wet edge and open time of coatings EASTMAN CHEM CO 2013-03-27 CN disclosed
CN-101223192-B Low molecular weight cellulose mixed esters and their use as low viscosity binders and modifiers in coating compositions EASTMAN CHEM CO 2013-01-16 CN disclosed
CN-102439095-A Refinish coating compositions comprising low molecular weight cellulose mixed esters EASTMAN CHEM CO 2012-05-02 CN disclosed
CN-101061192-B Aqueous coating compositions, coatings and methods comprising acetoacetyl-functional polymers VALSPAR SOURCING INC 2012-03-07 CN disclosed
CN-102307960-A Coating compositions containing acrylic and aliphatic polyester blends EASTMAN CHEM CO 2012-01-04 CN disclosed
CN-102276732-A Cellulose interpolymers and methods of oxidation 2011-12-14 CN disclosed
CN-102159654-A Basecoat compositions comprising low molecular weight cellulose mixed esters EASTMAN CHEM CO 2011-08-17 CN disclosed
CN-101528875-A Low-VOC additives to extend wet edge and open time of coatings EASTMAN CHEM CO (US) 2009-09-09 CN disclosed
CN-101223192-A Low molecular weight cellulose mixed esters and their use as low viscosity binders and modifiers in coating compositions EASTMAN CHEM CO (US) 2008-07-16 CN disclosed
CN-101061192-A Aqueous coating compositions, coatings and methods comprising acetoacetyl-functional polymers VALSPAR SOURCING INC (US) 2007-10-24 CN disclosed
CN-1886427-A Cellulose interpolymers and methods of oxidation EASTMAN CHEM CO (US) 2006-12-27 CN disclosed
CN-1474838-A Waterborne acrylic modified alkyd resins 伊斯曼化学公司 2004-02-11 CN disclosed
CN-1032013-C Process for making opaque, void-containing polymer particles ROHM & HAAS (US) 1996-06-12 CN disclosed
CN-1040039-A Absorbed the light tight polymer beads of multilayer of non-polymeric acid ROHM & HAAS (US) 1990-02-28 CN disclosed