Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34614 | 0.88 | CYP3A4 (0.45) | CYP3A4TDP1TP53ESR1ESR2 | |
| SCHEMBL28509714 | 0.86 | CYP3A4 (0.39) | CYP3A4TDP1TP53ESR1ESR2 | |
| SCHEMBL27863771 | 0.86 | CYP3A4 (0.39) | CYP3A4TDP1TP53ESR1ESR2 | |
| SCHEMBL5278199 | 0.85 | CYP3A4 (0.43) | CYP3A4TDP1TP53ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL11570696 | 0.85 | CYP3A4 (0.43) | CYP3A4TDP1TP53ESR1ESR2 | |
| SCHEMBL3749691 | 0.85 | CYP3A4 (0.43) | CYP3A4TDP1TP53ESR1ESR2 | |
| Ammonia Solution, Strong SCHEMBL15124087 | 0.85 | CYP3A4 (0.43) | CYP3A4TDP1TP53ESR1ESR2 | |
| SCHEMBL8384147 | 0.85 | CYP3A4 (0.43) | CYP3A4TDP1TP53ESR1ESR2 | |
| Propane SCHEMBL8522373 | 0.85 | TDP1 (0.43) | CYP3A4TDP1TP53ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL11570690 | 0.85 | CYP3A4 (0.43) | CYP3A4TDP1TP53ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445882-A1 | PROCESS FOR THE PREPARATION OF ARYLPYRIDINYL COMPOUNDS | Prime European Therapeuticals S.p.A. in forma abbreviata Euticals S.p.A. (IT) | 2012-05-02 | — | — | EP | disclosed |
| WO-2010149356-A1 | PROCESS FOR THE PREPARATION OF ARYLPYRIDINYL COMPOUNDS | PRIME EUROPEAN THERAPEUTICALS S.P.A. (IT) | 2010-12-29 | — | — | WO | disclosed |
| EP-0759024-A1 | PROCESS FOR PREPARING INTERMEDIATES FOR THE SYNTHESIS OF ANTIFUNGAL AGENTS | SCHERING CORPORATION (US) | 1997-02-26 | — | — | EP | disclosed |
| WO-1995030638-A1 | PROCESS FOR PREPARING INTERMEDIATES FOR THE SYNTHESIS OF ANTIFUNGAL AGENTS | SCHERING CORPORATION (US) | 1995-11-16 | — | — | WO | disclosed |