Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22599399 | 0.91 | HSD17B10 (0.38) | HSD17B10ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL27330609 | 0.90 | HSD17B10 (0.67) | HSD17B10ALDH1A1SMN1; SMN2KDM4EALOX15 | |
| SCHEMBL27303608 | 0.88 | HSD17B10 (0.69) | HSD17B10ALDH1A1SMN1; SMN2KDM4EALOX15 | |
| SCHEMBL27018306 | 0.88 | HSD17B10 (0.69) | HSD17B10ALDH1A1SMN1; SMN2KDM4EALOX15 | |
| SCHEMBL26272100 | 0.88 | HSD17B10 (0.69) | HSD17B10ALDH1A1SMN1; SMN2KDM4EALOX15 | |
| SCHEMBL29299565 | 0.84 | HSD17B10 (0.59) | HSD17B10ALDH1A1SMN1; SMN2KDM4EALOX15 | |
| SCHEMBL12158507 | 0.82 | KDM4E (0.55) | HSD17B10ALDH1A1SMN1; SMN2KDM4EALOX15 | |
| SCHEMBL26270951 | 0.81 | HSD17B10 (0.54) | HSD17B10ALDH1A1SMN1; SMN2KDM4EALOX15 | |
| SCHEMBL24220956 | 0.80 | HSD17B10 (0.47) | HSD17B10ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL21764427 | 0.80 | HSD17B10 (0.47) | HSD17B10ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129600-A1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR (GNRHR) TARGETED THERAPEUTICS AND USES THEREOF | RADIONETICS ONCOLOGY, INC. (US) | 2024-06-20 | — | — | WO | disclosed |