Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7642152 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL442135 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL439665 | 0.84 | CYP11B1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL439266 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL438850 | 0.82 | — | — | |
| Bromide SCHEMBL3692861 | 0.81 | — | — | |
| SCHEMBL7910511 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL8679220 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL7948420 | 0.80 | — | — | |
| SCHEMBL5704360 | 0.79 | CYP11B1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618912-B2 | Preparation of supported catalyst systems | BASELL POLYOLEFINE GMBH (DE) | 2009-11-17 | — | — | US | claimed |
| US-20060166813-A1 | Preparation of supported catalyst systems | BASELL POLYOLEFINE GMBH (DE) | 2006-07-27 | — | — | US | claimed |
| EP-1824888-B1 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2017-01-18 | — | — | EP | disclosed |
| EP-1740626-B1 | CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, ITS PRODUCTION AND USE | BASELL POLYOLEFINE GMBH (DE) | 2014-10-22 | — | — | EP | disclosed |
| US-8680001-B2 | Preparation of supported catalyst systems containing reduced amounts of aluminoxanes | BASELL POLYOLEFINE GMBH (DE) | 2014-03-25 | — | — | US | disclosed |
| US-8399536-B2 | Irradiated polyolefin composition comprising a non-phenolic stabilizer | Basell Poliolefine Italia, s.r.l. (IT) | 2013-03-19 | — | — | US | disclosed |
| EP-2173778-B1 | CATALYST SYSTEM FOR POLYMERIZATION OF OLEFINIC MONOMERS, PROCESS FOR PREPARING POLYMERS AND POLYMERS PREPARED BY THE PROCESS | BASELL POLYOLEFINE GMBH (DE) | 2012-04-18 | — | — | EP | disclosed |
| US-8133832-B2 | Catalyst system for polymerization of olefinic monomers, process for preparing polymers, and polymers prepared by the process | BASELL POLYOLEFINE GMBH (DE) | 2012-03-13 | — | — | US | disclosed |
| US-7973114-B2 | Monocyclopentadienyl complexes | BASELL POLYOLEFINE GMBH (DE) | 2011-07-05 | — | — | US | disclosed |
| EP-2275453-A1 | Latent metallocene catalyst systems for olefin polymerization | Ineos USA LLC (US) | 2011-01-19 | — | — | EP | disclosed |
| EP-1861409-B1 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2011-01-19 | — | — | EP | disclosed |
| US-5753773-A | HOMO OR COPOLYMERIZING PROPYLENE WITH ZERO TO 5% C2 TO C10 ALKENES THEN CONDUCTING SECOND POLYMERIZATION IN PRESENCE OF C2 TO C10 ALKENE IN PRESENCE OF METALLOCENE COMPLEX OF METALS OF SUBGROUP 4 AND 5 AND ALUMINOXANE CATALYSTS | BASF AKTIENGESELLSCHAFT (DE) | 1998-05-19 | — | — | US | disclosed |
| US-5688881-A | Oligomers and polymers of aminoalkenes | BASF AKTIENGESELLSCHAFT (DE) | 1997-11-18 | — | — | US | disclosed |
| US-5639839-A | Oligomers and polymers of aminoalkenes | BASF AKTIENGESELLSCHAFT (DE) | 1997-06-17 | — | — | US | disclosed |
| US-5514760-A | Soluble catalyst systems for the preparation of polyalk-1-enes having high molecular weights | BASF AKTIENGESELLSCHAFT (DE) | 1996-05-07 | — | — | US | disclosed |
| US-5483002-A | METALLOCENE POLYMERIZATION CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 1996-01-09 | — | — | US | disclosed |
| US-5474961-A | Mixed with alumoxane and organic halide, reverse deactivation | BASF AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |
| US-5457171-A | Metallocene complex of metal of subgroup IV or V, alumoxane and cyclic boron compound | BASF AKTIENGESELLSCHAFT (DE) | 1995-10-10 | — | — | US | disclosed |
| US-5453475-A | Process for preparing low density ethylene copolymers | BASF AKTIENGESELLSCHAFT (DE) | 1995-09-26 | — | — | US | disclosed |
| US-5296434-A | Soluble catalyst systems for the preparation of polyalk-1-enes having high molecular weights | BASF AKTIENGESELLSCHAFT (DE) | 1994-03-22 | — | — | US | disclosed |