Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30993813 | 1.00 | GPBAR1 (0.38) | GPBAR1AAK1RAB9AL3MBTL1PIK3CA | |
| SCHEMBL3336379 | 0.91 | GPBAR1 (0.38) | GPBAR1AAK1RAB9AL3MBTL1MAPT | |
| SCHEMBL27333195 | 0.85 | BCHE (0.38) | GPBAR1AAK1POLB | |
| SCHEMBL30993817 | 0.85 | BCHE (0.38) | GPBAR1AAK1POLB | |
| SCHEMBL3340863 | 0.85 | AAK1 (0.34) | GPBAR1AAK1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL19548416 | 0.85 | AAK1 (0.34) | GPBAR1AAK1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL30993851 | 0.83 | GPBAR1 (0.42) | GPBAR1RAB9AL3MBTL1PIK3CAMAPT | |
| SCHEMBL19548414 | 0.77 | AAK1 (0.32) | AAK1LIPE | |
| SCHEMBL3338200 | 0.77 | MAPT (0.41) | GPBAR1L3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3342113 | 0.76 | AAK1 (0.35) | AAK1L3MBTL1MAPTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129600-A1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR (GNRHR) TARGETED THERAPEUTICS AND USES THEREOF | RADIONETICS ONCOLOGY, INC. (US) | 2024-06-20 | — | — | WO | disclosed |