Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.45 |
| ▸ | RARG | P13631 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28926985 | 0.85 | KAT8 (0.54) | KAT8HPGDPPARANPC1MAPK1 | |
| SCHEMBL13536264 | 0.84 | KAT8 (0.63) | KAT8HPGDPPARANPC1MAPK1 | |
| SCHEMBL27506119 | 0.83 | KAT8 (0.41) | KAT8PPARARARBALDH1A1AKR1C2 | |
| SCHEMBL9253099 | 0.82 | HMGB1 (0.67) | KAT8HPGDPPARANPC1MAPK1 | |
| SCHEMBL27531558 | 0.81 | KAT8 (0.44) | KAT8PPARARARBAKR1C2AKR1C1 | |
| SCHEMBL27508131 | 0.81 | KAT8 (0.44) | KAT8PPARARARBPPARGGPR84 | |
| SCHEMBL28515541 | 0.81 | KAT8 (0.48) | KAT8HPGDPPARANPC1MAPK1 | |
| SCHEMBL5676629 | 0.80 | PPARA (0.62) | KAT8HPGDPPARANPC1MAPK1 | |
| SCHEMBL20503286 | 0.80 | KAT8 (0.62) | KAT8HPGDPPARARARBALDH1A1 | |
| SCHEMBL10947807 | 0.79 | HMGB1 (0.47) | KAT8RAB9AALDH1A1METAP2GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1086693-C | Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICAL CO LTD (JP) | 2002-06-26 | — | — | CN | disclosed |
| CN-1215722-A | Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS (JP) | 1999-05-05 | — | — | CN | disclosed |
| CN-1215721-A | Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS (JP) | 1999-05-05 | — | — | CN | disclosed |
| CN-1042530-C | Process for producing alkylsulfinylbenzamides | SUMITOMO SEIKA CHEMICALS (JP) | 1999-03-17 | — | — | CN | disclosed |
| CN-1107837-A | Process for producing alkylsulfinylbenzamides and 1, 2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS (JP) | 1995-09-06 | — | — | CN | disclosed |