SCHEMBL273374

SCHEMBL273374

CC1=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc2C1[Zr](Cl)(Cl)(C1C(C)=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc21)[SiH](C)C

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.31
CREBBP Q92793 1/20 0.31
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22419023 0.94
SCHEMBL3398059 0.92
SCHEMBL23528110 0.92
SCHEMBL89570 0.92
SCHEMBL5689984 0.91
SCHEMBL15809182 0.91
SCHEMBL3395843 0.90
SCHEMBL22419024 0.89
SCHEMBL7194942 0.89
SCHEMBL272367 0.89 NR1H4 (0.31) BRD4CREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1799726-B1 TRIALKYLALUMINUM TREATED SUPPORTS EXXONMOBIL CHEM PATENTS INC (US) 2011-07-13 EP claimed
US-7816456-B2 Semicrystalline propylene polymer composition for producing biaxially stretched polypropylene films BASELL POLYOLEFINE GMBH (DE) 2010-10-19 US claimed
US-7741417-B2 Preparation of polymerization catalyst activators utilizing indole-modified silica supports EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-06-22 US claimed
US-7618912-B2 Preparation of supported catalyst systems BASELL POLYOLEFINE GMBH (DE) 2009-11-17 US claimed
US-7385015-B2 Trialkylaluminum treated supports EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-06-10 US claimed
EP-1799726-A1 TRIALKYLALUMINUM TREATED SUPPORTS Exxonmobil Chemical Patents Inc. (US) 2007-06-27 EP claimed
US-20070117940-A1 Semicrystalline propylene polymer composition for producing biaxially stretched polypropylene films LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2007-05-24 US claimed
US-7220695-B2 Supported activator EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-22 US claimed
US-20070055028-A1 Preparation of polymerization catalyst activators utilizing indole-modified silica supports EXXONMOBIL CHEMICAL PATENTS INC. 2007-03-08 US claimed
US-20060166813-A1 Preparation of supported catalyst systems BASELL POLYOLEFINE GMBH (DE) 2006-07-27 US claimed
WO-2006044058-A1 TRIALKYLALUMINUM TREATED SUPPORTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-04-27 WO claimed
US-20060079394-A1 Trialkylaluminum treated supports EXXONMOBIL CHEMICAL PATENTS INC. 2006-04-13 US claimed
EP-1252202-B1 PARTLY CRYSTALLINE PROPYLENE POLYMERISATE COMPOSITION FOR PRODUCTION OF BIAXIAL-STRETCHED POLYPROPYLENE FILMS BASELL POLYOLEFINE GMBH (DE) 2006-02-22 EP claimed
US-20050148743-A1 polymerization catalyst systems comprising an ion-exchange layered silicate, an organoaluminum compound, and a heterocyclic compound EXXONMOBIL CHEMICAL PATENTS INC. 2005-07-07 US claimed
US-20030130443-A1 Partly crystalline propylene polymerisate composition for production of biaxial-stretched polypropylene films BASELL POLYOLEFINE GMBH (DE) 2003-07-10 US claimed
EP-1054911-B1 CATALYST SYSTEM, METHOD FOR THE PRODUCTION THEREOF AND ITS USE FOR THE POLYMERIZATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2003-01-22 EP claimed
US-6350830-B1 SUPPORTED POLYMERIZATION CATALYSTS TAGOR GMBH (DE) 2002-02-26 US claimed
US-20230323101-A1 POLYPROPYLENE COMPOSITIONS TOTALENERGIES ONETECH BELGIUM (BE) 2023-10-12 US disclosed
US-6417302-B1 REACTION PRODUCT OF DI(PENTAFLUOROPHENYL) BORINIC ACID AND ORGANOALUMINUM COMPOUND; OLEFIN POLYMERIZATION COORDINATION CATALYSTS BASELL POLYOLEFINE GMBH (DE) 2002-07-09 US disclosed
US-6350830-B1 SUPPORTED POLYMERIZATION CATALYSTS TAGOR GMBH (DE) 2002-02-26 US disclosed