Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28735117 | 0.85 | IDO1 (0.62) | IDO1ALDH1A1LMNAHTTTAS1R3 | |
| SCHEMBL18817861 | 0.84 | IDO1 (0.60) | IDO1ALDH1A1HTTFFAR1BLM | |
| SCHEMBL28016432 | 0.83 | IDO1 (0.63) | IDO1ALDH1A1HTTFFAR1BLM | |
| SCHEMBL26419665 | 0.83 | IDO1 (0.58) | IDO1ALDH1A1HTTTAS1R3TAS1R1 | |
| SCHEMBL4455923 | 0.83 | IDO1 (0.58) | IDO1ALDH1A1HTTTAS1R3TAS1R1 | |
| SCHEMBL30290988 | 0.83 | IDO1 (0.58) | IDO1ALDH1A1HTTTAS1R3TAS1R1 | |
| SCHEMBL15412376 | 0.83 | IDO1 (0.58) | IDO1ALDH1A1HTTTAS1R3TAS1R1 | |
| SCHEMBL27627307 | 0.82 | IDO1 (0.54) | IDO1ALDH1A1HTTTAS1R3TAS1R1 | |
| SCHEMBL30786788 | 0.81 | IDO1 (0.47) | IDO1FFAR1TSHRDRD3 | |
| SCHEMBL9722001 | 0.80 | IDO1 (0.55) | IDO1ALDH1A1LMNAHTTTAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1046713-C | Tetrahydroisoquinoline compounds, pharmaceutical compositions containing them, and their preparation and use | KNORR CO LTD (GB) | 1999-11-24 | — | — | CN | disclosed |
| CN-1128992-A | Therapeutic agents | KNORR CO LTD (DE) | 1996-08-14 | — | — | CN | disclosed |