SCHEMBL27337673

SCHEMBL27337673

CCCc1nc(-c2ccc(C)c(NC(=O)c3cnc4ccccn34)c2)no1

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIT P10721 20/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14741442 0.93 KIT (0.79) KIT
SCHEMBL21387286 0.93 KIT (0.80) KIT
SCHEMBL14757491 0.92 KIT (0.78) KIT
SCHEMBL14741798 0.92 KIT (0.73) KIT
SCHEMBL14741553 0.92 KIT (0.75) KIT
SCHEMBL14741582 0.92 KIT (0.77) KIT
SCHEMBL14741815 0.92 KIT (0.77) KIT
SCHEMBL14739088 0.91 KIT (0.80) KIT
SCHEMBL14741716 0.91 KIT (0.74) KIT
SCHEMBL14757518 0.91 KIT (0.78) KIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024124002-A1 COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS THIRD HARMONIC BIO, INC. (US) 2024-06-13 WO disclosed