Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27347786 | 0.86 | CNR2 (0.36) | CNR2NPC1 | |
| SCHEMBL27338733 | 0.84 | CNR2 (0.47) | CNR2MAPTKDM4EALDH1A1GAA | |
| SCHEMBL8521342 | 0.83 | CNR2 (0.44) | CNR2MAPTKDM4EALDH1A1GAA | |
| SCHEMBL9867679 | 0.67 | CNR2 (0.65) | CNR2MAPTKDM4EALDH1A1GAA | |
| SCHEMBL4138620 | 0.65 | CNR2 (0.62) | CNR2MAPTKDM4EALDH1A1GAA | |
| SCHEMBL7502719 | 0.65 | CYSLTR2 (0.63) | MAPTKDM4EALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7502713 | 0.65 | CYSLTR2 (0.63) | MAPTKDM4EALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2400093 | 0.64 | MGAM (0.61) | CNR2MAPTKDM4EALDH1A1GAA | |
| SCHEMBL1163452 | 0.64 | MGAM (0.61) | CNR2MAPTKDM4EALDH1A1GAA | |
| SCHEMBL4848224 | 0.64 | CYSLTR1 (0.76) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1061413-A | Medicinal compound | LILLY INDUSTRIES LTD (GB) | 1992-05-27 | — | — | CN | disclosed |