Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.92 |
| ▸ | PIK3CG | P48736 | 15/20 | 0.92 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.92 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.92 |
| ▸ | PIK3R1 | P27986 | 7/20 | 0.70 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29369878 | 0.96 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL2731875 | 0.96 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL29746153 | 0.96 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| Hydrochloric Acid SCHEMBL15226244 | 0.95 | PIK3CD (0.99) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| Bromide SCHEMBL15226533 | 0.95 | PIK3CD (0.99) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL19271671 | 0.95 | PIK3CD (0.96) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL19313983 | 0.91 | PIK3CD (0.90) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL31655834 | 0.90 | PIK3CD (0.90) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL11909221 | 0.90 | PIK3CD (0.90) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL15226457 | 0.90 | PIK3CD (0.88) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2630149-A1 | QUINAZOLIN-4 (3H) -ONE DERIVATIVES USED AS PI3 KINASE INHIBITORS | Respivert Limited (GB) | 2013-08-28 | — | — | EP | disclosed |
| WO-2012052753-A1 | QUINAZOLIN-4 (3H) -ONE DERIVATIVES USED AS PI3 KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2012-04-26 | — | — | WO | disclosed |