Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23931084 | 0.87 | USP30 (0.49) | USP30NR1H2USP2SMN1; SMN2EPHX1 | |
| SCHEMBL23931025 | 0.87 | USP30 (0.49) | USP30NR1H2USP2SMN1; SMN2EPHX1 | |
| SCHEMBL18471329 | 0.87 | USP30 (0.49) | USP30NR1H2USP2SMN1; SMN2EPHX1 | |
| SCHEMBL23931026 | 0.87 | USP30 (0.49) | USP30NR1H2USP2SMN1; SMN2EPHX1 | |
| SCHEMBL23931024 | 0.87 | USP30 (0.49) | USP30NR1H2USP2SMN1; SMN2EPHX1 | |
| SCHEMBL31208839 | 0.81 | USP30 (0.47) | USP30NR1H2USP2SMN1; SMN2EPHX1 | |
| SCHEMBL31209548 | 0.81 | USP30 (0.47) | USP30NR1H2USP2SMN1; SMN2EPHX1 | |
| SCHEMBL31208625 | 0.81 | USP30 (0.47) | USP30NR1H2USP2SMN1; SMN2EPHX1 | |
| SCHEMBL15764146 | 0.80 | NR1H2 (0.58) | USP30NR1H2USP2SMN1; SMN2EPHX1 | |
| SCHEMBL13801217 | 0.80 | NR1H2 (0.58) | USP30NR1H2USP2SMN1; SMN2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235691-A1 | BTK REDUCING MOLECULES FOR TREATMENT OF CANCERS AND IMMUNE SYSTEM DISORDERS | ACCUTAR BIOTECHNOLOGY, INC. (US) | 2023-12-07 | — | — | WO | disclosed |