Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 15/20 | 0.61 |
| ▸ | NPY1R | P25929 | 9/20 | 0.61 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.51 |
| ▸ | NPY2R | P49146 | 5/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27347693 | 1.00 | NPY4R (0.61) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL30434218 | 0.90 | NPY4R (0.59) | NPY4RNPY1RNPY5RNPY2RERAP2 | |
| Hydrochloric Acid SCHEMBL29508688 | 0.88 | NPY4R (0.58) | NPY4RNPY1RNPY5RNPY2RERAP2 | |
| SCHEMBL29947050 | 0.88 | NPY4R (0.59) | NPY4RNPY1RNPY5RNPY2R | |
| Hydrochloric Acid SCHEMBL30380134 | 0.88 | NPY4R (0.58) | NPY4RNPY1RNPY5RNPY2RERAP2 | |
| Hydrochloric Acid SCHEMBL29726986 | 0.88 | NPY4R (0.58) | NPY4RNPY1RNPY5RNPY2RERAP2 | |
| SCHEMBL29492562 | 0.87 | NPY4R (0.53) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL30379845 | 0.87 | NPY4R (0.63) | NPY4RNPY1RNPY5RNPY2RERAP2 | |
| SCHEMBL18671821 | 0.87 | NPY4R (0.52) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL29492567 | 0.87 | NPY4R (0.53) | NPY4RNPY1RNPY5RNPY2RFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1062536-A | Retroviral protease inhibitors from 3-chloro-2-chloromethyl-1-propylene derived | AMERICAN CYANAMID CO (US) | 1992-07-08 | — | — | CN | disclosed |