Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 6/20 | 0.59 |
| ▸ | TNF | P01375 | 2/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16327986 | 0.96 | TLR2 (0.59) | TLR2TNFMDM2HDAC1HDAC2 | |
| SCHEMBL27353660 | 0.91 | TLR2 (0.51) | TLR2TNFMDM2HDAC1HDAC2 | |
| SCHEMBL27353663 | 0.91 | TLR2 (0.51) | TLR2TNFMDM2HDAC1HDAC2 | |
| SCHEMBL27093964 | 0.91 | TLR2 (0.62) | TLR2TNF | |
| SCHEMBL27093960 | 0.91 | TLR2 (0.62) | TLR2TNF | |
| SCHEMBL30824273 | 0.90 | TLR2 (0.55) | TLR2TNFHDAC1HDAC2 | |
| SCHEMBL9654639 | 0.90 | TLR2 (0.54) | TLR2MDM2 | |
| SCHEMBL15203241 | 0.90 | TLR2 (0.54) | TLR2TNFMDM2 | |
| SCHEMBL10026043 | 0.89 | TLR2 (0.58) | TLR2TNFMDM2 | |
| SCHEMBL27353661 | 0.89 | TLR2 (0.51) | TLR2TNFMDM2HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208922-A1 | A TRIFLUOROMETHYL THIANTHRENIUM COMPOUND, PROCESS FOR PREPARING THE SAME AND THE USE THEREOF | STUDIENGESELLSCHAFT KOHLE GGMBH (DE) | 2024-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208922-A1 | A TRIFLUOROMETHYL THIANTHRENIUM COMPOUND, PROCESS FOR PREPARING THE SAME AND THE USE THEREOF | CYP4F3, GTF3C3, GTF3C4 | TLR2 4302/4885TNF 4587/4885MDM2 3655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.