Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PDE8B | O95263 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.42 |
| ▸ | FPR3 | P25089 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | AHCY | P23526 | 1/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27353389 | 1.00 | KDM1A (0.48) | KDM1ASMN1; SMN2PDE8BATMOPRD1 | |
| SCHEMBL27353638 | 1.00 | KDM1A (0.48) | KDM1ASMN1; SMN2PDE8BATMOPRD1 | |
| SCHEMBL18872558 | 0.96 | SMN1; SMN2 (0.47) | KDM1ASMN1; SMN2ATMOPRD1ALDH1A1 | |
| SCHEMBL2486249 | 0.96 | SMN1; SMN2 (0.47) | KDM1ASMN1; SMN2ATMOPRD1ALDH1A1 | |
| SCHEMBL27353429 | 0.89 | KDM1A (0.47) | KDM1ASMN1; SMN2PDE8BATMOPRD1 | |
| SCHEMBL27353413 | 0.89 | KDM1A (0.47) | KDM1ASMN1; SMN2PDE8BATMOPRD1 | |
| SCHEMBL27353410 | 0.89 | KDM1A (0.47) | KDM1ASMN1; SMN2PDE8BATMOPRD1 | |
| SCHEMBL24335833 | 0.86 | KDM1A (0.47) | KDM1ASMN1; SMN2PDE8BATMOPRD1 | |
| SCHEMBL5654694 | 0.86 | KDM1A (0.50) | KDM1ASMN1; SMN2PDE8BATMOPRD1 | |
| SCHEMBL1244838 | 0.86 | KDM1A (0.50) | KDM1ASMN1; SMN2PDE8BATMOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393918-A1 | SELF DEGRADATION-TYPE CDK9 INHIBITOR PRODRUG AND LIPOSOME ENCAPSULATING SAME | Sumitomo Pharma Co., Ltd. (JP) | 2024-07-03 | — | — | EP | disclosed |