Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 4/20 | 0.59 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.53 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 5/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27355193 | 0.89 | STAT3 (0.63) | STAT3CRBNCA2HDAC1HDAC2 | |
| SCHEMBL31719694 | 0.89 | STAT3 (0.62) | STAT3CRBNCA2HDAC1HDAC2 | |
| SCHEMBL29992547 | 0.83 | STAT3 (0.66) | STAT3CRBNCA2HDAC1HDAC2 | |
| SCHEMBL22291621 | 0.83 | STAT3 (0.66) | STAT3CRBNCA2HDAC1HDAC2 | |
| SCHEMBL23298703 | 0.83 | STAT3 (0.66) | STAT3CRBNCA2HDAC1HDAC2 | |
| SCHEMBL23298707 | 0.83 | STAT3 (0.66) | STAT3CRBNCA2HDAC1HDAC2 | |
| SCHEMBL31436672 | 0.83 | STAT3 (0.66) | STAT3CRBNCA2HDAC1HDAC2 | |
| SCHEMBL31474307 | 0.83 | STAT3 (0.66) | STAT3CRBNCA2HDAC1HDAC2 | |
| SCHEMBL31424943 | 0.83 | CRBN (0.60) | STAT3CRBNCA2HDAC1HDAC2 | |
| SCHEMBL23298705 | 0.82 | STAT3 (0.65) | STAT3CRBNCA2HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006742-A2 | NRF2 PROTEIN DEGRADERS | DRACEN PHARMACEUTICALS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |