Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALB | P02768 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | GNPAT | O15228 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2735590 | 0.95 | FOLH1 (0.50) | FOLH1SMN1; SMN2ALBEPHX1SIRT6 | |
| SCHEMBL13057085 | 0.90 | FOLH1 (0.51) | FOLH1SMN1; SMN2EPHX1SIRT1TGM2 | |
| SCHEMBL10017794 | 0.90 | FOLH1 (0.51) | FOLH1SMN1; SMN2EPHX1SIRT1TGM2 | |
| SCHEMBL1200060 | 0.86 | FOLH1 (0.71) | FOLH1SMN1; SMN2ALBSIRT6SIRT1 | |
| SCHEMBL2735591 | 0.86 | FOLH1 (0.71) | FOLH1SMN1; SMN2ALBSIRT6SIRT1 | |
| SCHEMBL16393150 | 0.86 | FOLH1 (0.71) | FOLH1SMN1; SMN2ALBSIRT6SIRT1 | |
| SCHEMBL18206786 | 0.85 | MEN1 (0.61) | FOLH1SMN1; SMN2ALBMAPTALDH1A1 | |
| SCHEMBL10254699 | 0.85 | MEN1 (0.61) | FOLH1SMN1; SMN2ALBMAPTALDH1A1 | |
| SCHEMBL13026641 | 0.84 | FOLH1 (0.47) | FOLH1SMN1; SMN2EPHX1SIRT1GNPAT | |
| SCHEMBL15691994 | 0.82 | FOLH1 (0.50) | FOLH1SMN1; SMN2ALBSIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088884-B2 | Multi-armed forms of activated polyoxazoline and methods of synthesis thereof | SERINA THERAPEUTICS, INC. (US) | 2012-01-03 | — | — | US | disclosed |
| US-20100249368-A1 | Multi-Armed Forms of Activated Polyoxazoline and Methods of Synthesis Thereof | SERINA THERAPEUTICS, INC. (US) | 2010-09-30 | — | — | US | disclosed |