SCHEMBL27356017

SCHEMBL27356017

CC(C)(C)OC(=O)NC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ DPP9 Q86TI2 20/20 1.00
▸ DPP8 Q6V1X1 18/20 1.00
▸ GLMN Q92990 2/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30684985 1.00 DPP9 (1.00) DPP9DPP8GLMN
SCHEMBL30685144 0.90 DPP9 (0.82) DPP9DPP8GLMN
SCHEMBL27358121 0.90 DPP9 (0.82) DPP9DPP8GLMN
SCHEMBL30685018 0.89 DPP9 (1.00) DPP9DPP8GLMN
SCHEMBL27356266 0.89 DPP9 (1.00) DPP9DPP8GLMN
SCHEMBL30685006 0.88 DPP9 (1.00) DPP9DPP8GLMN
SCHEMBL30685231 0.88 DPP9 (0.79) DPP9DPP8GLMN
SCHEMBL27356426 0.88 DPP9 (0.79) DPP9DPP8GLMN
SCHEMBL27357672 0.88 DPP9 (0.78) DPP9DPP8GLMN
SCHEMBL27356189 0.85 DPP9 (1.00) DPP9DPP8GLMN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023233024-A1 DPP9 BINDING COMPOUNDS UNIVERSITEIT ANTWERPEN (BE) 2023-12-07 — — WO disclosed
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