SCHEMBL27356602

SCHEMBL27356602

CC1CC2CC(C)(NC(=O)OCCOCCNC(=O)OC(C)(C)C)CC(NCC(=O)N3Cc4ccc(F)cc4C3)(C1)C2

nearest known ligand 0.64

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ DPP9 Q86TI2 20/20 0.64
▸ DPP8 Q6V1X1 19/20 0.64
▸ DPP4 P27487 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27356629 0.93 DPP9 (0.65) DPP9DPP8DPP4
SCHEMBL27357379 0.93 DPP9 (0.62) DPP9DPP8DPP4
SCHEMBL30685189 0.90 DPP9 (0.80) DPP9DPP8DPP4
SCHEMBL27356607 0.86 DPP9 (0.65) DPP9DPP8DPP4
SCHEMBL30685087 0.85 DPP9 (0.78) DPP9DPP8DPP4
SCHEMBL27356635 0.84 DPP9 (0.79) DPP9DPP8DPP4
SCHEMBL27356302 0.83 DPP9 (0.76) DPP9DPP8
SCHEMBL30685101 0.82 DPP9 (0.79) DPP9DPP8DPP4
SCHEMBL27357387 0.82 DPP9 (0.79) DPP9DPP8DPP4
SCHEMBL27356672 0.80 DPP8 (0.83) DPP9DPP8DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023233024-A1 DPP9 BINDING COMPOUNDS UNIVERSITEIT ANTWERPEN (BE) 2023-12-07 — — WO disclosed
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