SCHEMBL27357222

SCHEMBL27357222

CC1CC2CC(C)(NC(=O)c3cnc4ccccc4c3)CC(NCC(=O)N3Cc4ccc(F)cc4C3)(C1)C2

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ DPP9 Q86TI2 19/20 0.52
▸ DPP8 Q6V1X1 17/20 0.52
▸ GLMN Q92990 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31732773 0.88 DPP9 (0.63) DPP9DPP8GLMN
SCHEMBL27358382 0.88 DPP9 (0.63) DPP9DPP8GLMN
Hydrochloric Acid SCHEMBL30685062 0.88 DPP9 (0.62) DPP9DPP8GLMN
SCHEMBL27357143 0.83 DPP9 (0.53) DPP9DPP8GLMN
SCHEMBL27357306 0.83 DPP9 (0.56) DPP9DPP8GLMN
SCHEMBL27357229 0.82 DPP9 (0.51) DPP9DPP8GLMN
SCHEMBL27357178 0.82 DPP9 (0.55) DPP9DPP8GLMN
SCHEMBL27355704 0.80 DPP9 (0.55) DPP9DPP8GLMN
SCHEMBL27357191 0.78 DPP9 (0.50) DPP9DPP8GLMN
SCHEMBL27356710 0.77 DPP9 (0.57) DPP9DPP8GLMN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023233024-A1 DPP9 BINDING COMPOUNDS UNIVERSITEIT ANTWERPEN (BE) 2023-12-07 — — WO disclosed
Send feedback