SCHEMBL27357688

SCHEMBL27357688

O=C(NC(c1ccccc1)c1ccccc1)OC12CC3CC1CC(NCC(=O)N1Cc4ccccc4C1)(C3)C2

nearest known ligand 0.76

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ DPP9 Q86TI2 20/20 0.76
▸ DPP8 Q6V1X1 19/20 0.76
▸ GLMN Q92990 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30685126 0.86 DPP8 (1.00) DPP9DPP8GLMN
SCHEMBL27356093 0.86 DPP8 (1.00) DPP9DPP8GLMN
SCHEMBL27357734 0.85 DPP8 (0.76) DPP9DPP8GLMN
SCHEMBL27357680 0.84 DPP9 (0.75) DPP9DPP8GLMN
SCHEMBL27357738 0.82 DPP9 (0.77) DPP9DPP8GLMN
SCHEMBL27356085 0.82 DPP9 (0.73) DPP9DPP8GLMN
SCHEMBL27356030 0.82 DPP9 (0.77) DPP9DPP8GLMN
SCHEMBL27356159 0.80 DPP8 (0.77) DPP9DPP8GLMN
SCHEMBL30685090 0.80 DPP8 (1.00) DPP9DPP8GLMN
SCHEMBL27356073 0.80 DPP8 (1.00) DPP9DPP8GLMN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023233024-A1 DPP9 BINDING COMPOUNDS UNIVERSITEIT ANTWERPEN (BE) 2023-12-07 — — WO disclosed
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