SCHEMBL27358201

SCHEMBL27358201

O=C(NC12CC3CC(CC(NCC(=O)N4Cc5ccc(F)cc5C4)(C3)C1)C2)c1ccc(-c2ccccc2)nc1

nearest known ligand 0.63

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ DPP8 Q6V1X1 20/20 0.63
▸ DPP9 Q86TI2 20/20 0.63
▸ GLMN Q92990 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31732788 1.00 DPP8 (0.63) DPP8DPP9GLMN
Hydrochloric Acid SCHEMBL30685290 0.99 DPP8 (0.62) DPP8DPP9GLMN
SCHEMBL30685070 0.90 DPP9 (0.69) DPP8DPP9GLMN
SCHEMBL27358197 0.90 DPP9 (0.69) DPP8DPP9GLMN
SCHEMBL27358204 0.90 DPP8 (0.62) DPP8DPP9GLMN
SCHEMBL31732780 0.90 DPP8 (0.62) DPP8DPP9GLMN
Hydrochloric Acid SCHEMBL30685122 0.90 DPP9 (0.68) DPP8DPP9GLMN
Hydrochloric Acid SCHEMBL30685119 0.89 DPP8 (0.62) DPP8DPP9GLMN
SCHEMBL27355724 0.89 DPP9 (0.64) DPP8DPP9GLMN
Hydrochloric Acid SCHEMBL30685263 0.88 DPP9 (0.63) DPP8DPP9GLMN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023233024-A1 DPP9 BINDING COMPOUNDS UNIVERSITEIT ANTWERPEN (BE) 2023-12-07 — — WO disclosed
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