Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.60 |
| ▸ | HTR6 | P50406 | 6/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | IL1RN | P18510 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27358419 | 1.00 | HDAC8 (0.69) | HDAC8MEN1KMT2ATHRBTDP1 | |
| SCHEMBL5020581 | 0.86 | HDAC8 (0.82) | HDAC8MEN1KMT2ATHRBTDP1 | |
| SCHEMBL13477817 | 0.83 | HDAC8 (0.81) | HDAC8MEN1KMT2ATHRBTDP1 | |
| SCHEMBL29487516 | 0.82 | HDAC8 (1.00) | HDAC8MEN1KMT2ATHRBTDP1 | |
| SCHEMBL1232657 | 0.82 | HDAC8 (1.00) | HDAC8MEN1KMT2ATHRBTDP1 | |
| SCHEMBL30702322 | 0.82 | HDAC8 (1.00) | HDAC8MEN1KMT2ATHRBTDP1 | |
| SCHEMBL1232655 | 0.82 | HDAC8 (1.00) | HDAC8MEN1KMT2ATHRBTDP1 | |
| SCHEMBL5020580 | 0.81 | HDAC8 (0.70) | HDAC8MEN1KMT2ATHRBTDP1 | |
| SCHEMBL8251666 | 0.81 | HDAC8 (0.70) | HDAC8MEN1KMT2ATHRBTDP1 | |
| SCHEMBL1403010 | 0.78 | HDAC8 (0.71) | HDAC8MEN1KMT2ATHRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023242278-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KIDNEY DISEASES | UNIVERSITÄTSMEDIZIN GREIFSWALD (DE) | 2023-12-21 | — | — | WO | disclosed |