Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 14/20 | 0.44 |
| ▸ | ELOC | Q15369 | 4/20 | 0.41 |
| ▸ | ELOB | Q15370 | 4/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30148979 | 0.88 | VHL (0.51) | VHLELOCELOBDPP4 | |
| SCHEMBL30149081 | 0.86 | VHL (0.43) | VHLELOCELOB | |
| SCHEMBL30772026 | 0.84 | VHL (0.49) | VHLELOCELOBDPP4 | |
| SCHEMBL27359853 | 0.83 | VHL (0.47) | VHLELOCELOBNAMPT | |
| SCHEMBL24757713 | 0.82 | VHL (0.51) | VHLELOCELOBDPP4 | |
| SCHEMBL24756803 | 0.82 | VHL (0.46) | VHLELOCELOBDPP4 | |
| SCHEMBL27359817 | 0.82 | VHL (0.68) | VHLELOCELOB | |
| SCHEMBL30149065 | 0.82 | VHL (0.52) | VHLELOCELOBDPP4 | |
| SCHEMBL24757855 | 0.82 | VHL (0.52) | VHLELOCELOBDPP4 | |
| SCHEMBL30771993 | 0.81 | VHL (0.51) | VHLELOCELOBDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024040080-A1 | KRAS INHIBITOR CONJUGATES | ERASCA, INC. (US) | 2024-02-22 | — | — | WO | disclosed |