Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 20/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27360088 | 0.94 | VHL (0.42) | VHL | |
| SCHEMBL27360082 | 0.91 | VHL (0.43) | VHL | |
| SCHEMBL27360078 | 0.84 | VHL (0.41) | VHL | |
| SCHEMBL27360076 | 0.83 | VHL (0.42) | VHL | |
| SCHEMBL27360160 | 0.83 | VHL (0.42) | VHL | |
| SCHEMBL27359853 | 0.82 | VHL (0.47) | VHL | |
| SCHEMBL27359852 | 0.78 | VHL (0.47) | VHL | |
| SCHEMBL27360086 | 0.78 | VHL (0.46) | VHL | |
| SCHEMBL30760141 | 0.78 | DPP4 (0.47) | VHL | |
| SCHEMBL27360153 | 0.77 | VHL (0.42) | VHL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024040080-A1 | KRAS INHIBITOR CONJUGATES | ERASCA, INC. (US) | 2024-02-22 | — | — | WO | disclosed |