Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 17/20 | 0.52 |
| ▸ | ELOC | Q15369 | 4/20 | 0.45 |
| ▸ | ELOB | Q15370 | 4/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30772070 | 0.87 | VHL (0.50) | VHLELOCELOBPDE2A | |
| SCHEMBL30771993 | 0.86 | VHL (0.51) | VHLELOCELOBPDE2A | |
| SCHEMBL30772055 | 0.86 | VHL (0.51) | VHLELOCELOBPDE2A | |
| SCHEMBL30771987 | 0.86 | VHL (0.51) | VHLELOCELOBPDE2A | |
| SCHEMBL27360238 | 0.85 | VHL (0.46) | VHLELOCELOB | |
| SCHEMBL27360146 | 0.84 | VHL (0.41) | VHLELOCELOBCASP1 | |
| SCHEMBL30772003 | 0.83 | VHL (0.48) | VHLELOCELOBPDE2A | |
| SCHEMBL30772022 | 0.82 | VHL (0.49) | VHLELOCELOB | |
| SCHEMBL27063075 | 0.80 | VHL (0.43) | VHLELOCELOBPDE2A | |
| SCHEMBL27359674 | 0.80 | VHL (0.58) | VHLELOCELOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024040080-A1 | KRAS INHIBITOR CONJUGATES | ERASCA, INC. (US) | 2024-02-22 | — | — | WO | disclosed |