Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 9/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27360354 | 0.93 | ELANE (0.39) | XIAPMLXELANETAAR1SLC6A2 | |
| SCHEMBL27360356 | 0.92 | XIAP (0.37) | XIAPMLXELANETAAR1SLC6A2 | |
| SCHEMBL27360246 | 0.92 | ELANE (0.40) | XIAPMLXPREPELANEROCK2 | |
| SCHEMBL27360367 | 0.91 | XIAP (0.38) | XIAPMLXPREPELANETAAR1 | |
| SCHEMBL27360361 | 0.91 | MAPK1 (0.38) | XIAPMLXPREPELANEMAPK1 | |
| SCHEMBL27360359 | 0.91 | XIAP (0.37) | XIAPMLXPREPELANETAAR1 | |
| SCHEMBL27360362 | 0.91 | ELANE (0.40) | XIAPMLXELANETAAR1 | |
| SCHEMBL27360580 | 0.90 | XIAP (0.38) | XIAPMLXPREPELANETAAR1 | |
| SCHEMBL27360364 | 0.90 | ELANE (0.37) | XIAPMLXPREPELANEGSK3B | |
| SCHEMBL27360245 | 0.89 | ELANE (0.41) | XIAPMLXELANETAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024040080-A1 | KRAS INHIBITOR CONJUGATES | ERASCA, INC. (US) | 2024-02-22 | — | — | WO | disclosed |