SCHEMBL27360353

SCHEMBL27360353

O=C(O)c1cc2ccccc2cn1.[NaH]

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 2/20 0.53
ALOX15 P16050 2/20 0.48
ALDH1A1 P00352 2/20 0.48
HPGD P15428 1/20 0.48
HSD17B10 Q99714 1/20 0.48
KMT2A Q03164 2/20 0.47
GABRP O00591 1/20 0.47
GABRD O14764 1/20 0.47
GABRA1 P14867 1/20 0.47
GABRB1 P18505 1/20 0.47
GABRG2 P18507 1/20 0.47
GABRB3 P28472 1/20 0.47
GABRA5 P31644 1/20 0.47
GABRA3 P34903 1/20 0.47
GABRA2 P47869 1/20 0.47
GABRB2 P47870 1/20 0.47
GABRA4 P48169 1/20 0.47
GABRE P78334 1/20 0.47
GABRA6 Q16445 1/20 0.47
GABRG1 Q8N1C3 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL155043 0.98 EGLN1 (0.54) EGLN1ALOX15ALDH1A1HPGDHSD17B10
SCHEMBL29746814 0.98 EGLN1 (0.54) EGLN1ALOX15ALDH1A1HPGDHSD17B10
SCHEMBL29489052 0.98 EGLN1 (0.54) EGLN1ALOX15ALDH1A1HPGDHSD17B10
Hydrochloric Acid SCHEMBL27469719 0.96 EGLN1 (0.53) EGLN1ALOX15ALDH1A1HPGDHSD17B10
Water SCHEMBL1201320 0.96 EGLN1 (0.53) EGLN1ALOX15ALDH1A1HPGDHSD17B10
Hydrochloric Acid SCHEMBL28181942 0.94 EGLN1 (0.51) EGLN1ALOX15ALDH1A1HPGDHSD17B10
Methyl Alcohol SCHEMBL28240452 0.94 EGLN1 (0.51) EGLN1ALOX15ALDH1A1HPGDHSD17B10
Acetic Acid SCHEMBL27950634 0.92 EGLN1 (0.50) EGLN1ALOX15ALDH1A1HPGDHSD17B10
Sulfuric Acid SCHEMBL2272707 0.91 EGLN1 (0.49) EGLN1ALOX15ALDH1A1HPGDHSD17B10
SCHEMBL27821497 0.90 EGFR (0.51) EGLN1ALOX15ALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1069314-C 2-oxoindoline derivatives TANABE SEIYAKU CO (JP) 2001-08-08 CN disclosed
CN-1136310-A 2-oxoindoline derivatives TANABE SEIYAKU CO (JP) 1996-11-20 CN disclosed