Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876041 | 0.83 | KMT2A (0.48) | MEN1TP53PABPC1KMT2ACSF1R | |
| SCHEMBL112350 | 0.83 | MEN1 (0.51) | MEN1TP53PABPC1KMT2ACSF1R | |
| SCHEMBL8970101 | 0.80 | MEN1 (0.51) | MEN1TP53PABPC1KMT2ACSF1R | |
| SCHEMBL27708062 | 0.77 | MEN1 (0.51) | MEN1TP53PABPC1KMT2ACSF1R | |
| SCHEMBL12413754 | 0.76 | TP53 (0.48) | MEN1TP53PABPC1KMT2ACSF1R | |
| SCHEMBL13111955 | 0.76 | MEN1 (0.48) | MEN1TP53PABPC1KMT2ACSF1R | |
| SCHEMBL7106613 | 0.75 | TDP1 (0.63) | MEN1KMT2ATDP1CYP11B1CYP11B2 | |
| SCHEMBL4019974 | 0.74 | MEN1 (0.49) | MEN1TP53PABPC1KMT2ACSF1R | |
| SCHEMBL4019976 | 0.74 | MEN1 (0.49) | MEN1TP53PABPC1KMT2ACSF1R | |
| SCHEMBL4022616 | 0.74 | MEN1 (0.52) | MEN1TP53PABPC1KMT2ACSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1059445-C | Novel derivatives of erythromycin, their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 2000-12-13 | — | — | CN | disclosed |
| CN-1126997-A | Novel erythromycin derivatives, method for preparing same and use thereof as drugs | ROUSSEL UCLAF (FR) | 1996-07-17 | — | — | CN | disclosed |