Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNG | P07510 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CHRND | Q07001 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 3/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31507302 | 1.00 | KMT2A (0.38) | KMT2ACHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL29237427 | 0.87 | CHRNA1 (0.42) | KMT2ACHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL30217022 | 0.87 | CHRNA1 (0.42) | KMT2ACHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL29237665 | 0.84 | KMT2A (0.41) | KMT2ACHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL30967820 | 0.84 | KMT2A (0.41) | KMT2ACHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL29841501 | 0.83 | KMT2A (0.35) | KMT2ACHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL30520809 | 0.83 | KMT2A (0.38) | KMT2ACHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL27361970 | 0.83 | KMT2A (0.35) | KMT2ACHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL22832485 | 0.83 | KMT2A (0.42) | KMT2ACHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL3206919 | 0.82 | KMT2A (0.45) | KMT2AOPRM1WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573085-A1 | SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS | Glenmark Pharmaceuticals Limited (IN) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024062363-A1 | BICYCLIC HETEROCYCLIC COMPOUNDS AS CBL-B INHIBITORS | GLENMARK PHARMACEUTICALS LTD (IN) | 2024-03-28 | — | — | WO | disclosed |
| WO-2024038378-A1 | SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS | GLENMARK PHARMACEUTICALS LTD (IN) | 2024-02-22 | — | — | WO | disclosed |
| WO-2024038378-A1 | SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS | GLENMARK PHARMACEUTICALS LTD (IN) | 2024-02-22 | — | — | WO | disclosed |