Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | C1R | P00736 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16527705 | 0.86 | IKBKB (0.57) | IKBKBSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL11626566 | 0.82 | IKBKB (0.72) | IKBKBSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL5539532 | 0.78 | TP53 (0.55) | IKBKBSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL5539525 | 0.76 | TP53 (0.52) | IKBKBSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL1436022 | 0.73 | MEN1 (0.53) | SMN1; SMN2TP53NPC1RAB9AHPGD | |
| SCHEMBL4970219 | 0.71 | IKBKB (0.53) | IKBKBSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL5544481 | 0.69 | NPC1 (0.52) | IKBKBSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL2792213 | 0.69 | IKBKB (0.51) | IKBKBSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL10590839 | 0.68 | KDM4E (0.58) | IKBKBSMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL10590832 | 0.68 | KDM4E (0.58) | IKBKBSMN1; SMN2NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1056372-C | Thiazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-09-13 | — | — | CN | disclosed |