SCHEMBL27362203

SCHEMBL27362203

CC(C)c1cccc(Oc2ccccc2-c2cn(C)c(=O)c3[nH]ccc23)c1

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27364175 0.86 BRD4 (0.79) BRD4
SCHEMBL15067633 0.86 BRD4 (1.00) BRD4
SCHEMBL27364458 0.83 BRD4 (0.59) BRD4
SCHEMBL25192302 0.83 BRD4 (0.77) BRD4
SCHEMBL27362155 0.82 BRD4 (0.80) BRD4
SCHEMBL30811947 0.77 BRD4 (0.54) BRD4
SCHEMBL22588261 0.77 BRD4 (0.77) BRD4
SCHEMBL22588297 0.77 BRD4 (0.77) BRD4
SCHEMBL22588079 0.77 BRD4 (0.77) BRD4
SCHEMBL30812050 0.76 BRD4 (0.62) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024054956-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE HALDA THERAPEUTICS OPCO, INC. (US) 2024-03-14 WO disclosed