Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 15/20 | 0.69 |
| ▸ | CFD | P00746 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.56 |
| ▸ | RELA | Q04206 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | TEC | P42680 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27363021 | 0.88 | MRGPRX4 (0.69) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL9301215 | 0.82 | MRGPRX4 (1.00) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL27363115 | 0.80 | MRGPRX4 (0.65) | MRGPRX4NR4A2 | |
| SCHEMBL27363026 | 0.79 | MRGPRX4 (0.60) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL27927703 | 0.79 | NR4A2 (0.63) | MRGPRX4RAB9ANR4A2 | |
| SCHEMBL4406160 | 0.77 | NR4A2 (0.87) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL7452285 | 0.77 | CYSLTR1 (0.77) | MRGPRX4 | |
| SCHEMBL22480788 | 0.77 | MRGPRX4 (1.00) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL27654985 | 0.77 | NR4A2 (0.70) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL7010090 | 0.76 | CYSLTR1 (0.84) | MRGPRX4NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235753-A2 | ALDH2 INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-12-07 | — | — | WO | disclosed |