Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA6 | P23280 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1808796 | 0.98 | MYC (0.44) | MYCTTRPNMTCYP1A2TSHR | |
| Fluoride SCHEMBL27713198 | 0.96 | MYC (0.43) | MYCTTRPNMTCYP1A2TSHR | |
| Water SCHEMBL3952739 | 0.96 | MYC (0.43) | MYCTTRPNMTCYP1A2TSHR | |
| Benzene SCHEMBL28759204 | 0.96 | SMN1; SMN2 (0.43) | MYCTTRPNMTCYP1A2TSHR | |
| Water SCHEMBL30187601 | 0.96 | MYC (0.43) | MYCTTRPNMTCYP1A2TSHR | |
| SCHEMBL1805940 | 0.82 | TAAR1 (0.50) | MYCTTRCYP1A2 | |
| SCHEMBL31425768 | 0.80 | MYC (0.47) | MYCTTRCYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL31425767 | 0.80 | MYC (0.47) | MYCTTRCYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL14991455 | 0.80 | MYC (0.47) | MYCTTRCYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL30446463 | 0.80 | MYC (0.47) | MYCTTRCYP1A2TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1137085-C | Process for preparation of 5,6-dihydroxyl-2-amino-1,2,3,4-tetrahydronaphthalene derivatives | ������˹ҩƷ��˾ | 2004-02-04 | — | — | CN | disclosed |
| CN-1073984-C | Process for preparing 5, 6-dihydroxy-2-amino-1, 2,3, 4-tetrahydronaphthalene derivatives | CHIESI FARMA SPA (IT) | 2001-10-31 | — | — | CN | disclosed |
| CN-1278526-A | Process for preparation of 5,6-dihydroxyl-2-amino-1,2,3,4-tetrahydronaphthalene derivatives | CHIESI PHARMACEUTICAL S P A (IT) | 2001-01-03 | — | — | CN | disclosed |
| CN-1278528-A | Process for preparation of 5,6-dihydroxyl-2-amino-1,2,3,4-tetrahydronaphthalene derivatives | CHIESI PHARMACEUTICAL S P A (IT) | 2001-01-03 | — | — | CN | disclosed |
| CN-1278527-A | Process for preparation of 5,6-dihydrxyl-2-amino-1,2,3,4-tetrahydronaphthalene derivatives | CHIESI PHARMACEUTICAL S P A (IT) | 2001-01-03 | — | — | CN | disclosed |
| CN-1147808-A | Process for preparing 5, 6-dihydroxy-2-amino-1, 2, 3, 4-tetrahydronaphthalene derivatives | CHIESI FARMA SPA (IT) | 1997-04-16 | — | — | CN | disclosed |