⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14775352 | 0.72 | — | — | |
| SCHEMBL27648099 | 0.69 | — | — | |
| SCHEMBL27642555 | 0.67 | — | — | |
| SCHEMBL27481322 | 0.67 | — | — | |
| SCHEMBL27436873 | 0.67 | — | — | |
| SCHEMBL27354680 | 0.67 | — | — | |
| SCHEMBL14775482 | 0.67 | — | — | |
| SCHEMBL27502085 | 0.67 | — | — | |
| SCHEMBL19285567 | 0.67 | — | — | |
| SCHEMBL27876346 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104193731-A | Novel carbamide substituted biphenyl compound, composition and application thereof | GUANGDONG HEC PHARMACEUTICAL | 2014-12-10 | — | — | CN | claimed |
| CN-101163678-A | Pyridylmethylsulfone derivative | DAIICHI SANKYO CO LTD (JP) | 2008-04-16 | — | — | CN | claimed |
| CN-1221534-C | Substituted 8-arylquinoline phosphodiesterase-4 inhibitors | MERCK FROSST CANADA INC (CA) | 2005-10-05 | — | — | CN | claimed |
| CN-1230187-A | Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors | GLAXO GROUP LTD (GB) | 1999-09-29 | — | — | CN | claimed |
| CN-116196411-A | PAPD5 and PAPD7 inhibitors for the treatment of hepatitis B infection | 豪夫迈·罗氏有限公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-110114358-A | Novel compound and pharmacologically acceptable salt thereof | 明治制果药业株式会社 | 2019-08-09 | — | — | CN | disclosed |
| CN-108601774-A | Combination for the treatment of RSV | 爱尔兰詹森科学公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-108602908-A | Support type composite catalyst and the method for preparing olefin polymer using it | LG化学株式会社 | 2018-09-28 | — | — | CN | disclosed |
| CN-105899508-B | Novel dihydroquinolizinones for the treatment and prophylaxis of hepatitis b virus infection | 豪夫迈·罗氏有限公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-106660991-A | Antiproliferative compounds and methods of use thereof | 细胞基因公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-104540817-B | 1,3 dihydro 2H benzimidazole 2 ketone derivatives as the use heterocyclic substituted of respiratory syncytial virus antiviral agent | 爱尔兰詹森科学公司 | 2017-03-01 | — | — | CN | disclosed |
| CN-105899508-A | Novel dihydroquinolizinones for the treatment and prophylaxis of hepatitis B virus infection | 豪夫迈·罗氏有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-1922160-A | Compound (I) | ASTRAZENECA AB (SE) | 2007-02-28 | — | — | CN | disclosed |
| CN-1922159-A | Benzamide derivatives and their use as glucokinase activating agents | ASTRAZENECA AB (SE) | 2007-02-28 | — | — | CN | disclosed |
| CN-1806016-A | Use of quinaldine and naphthaline derivatives as crystallisation modifiers | BASF AG (DE) | 2006-07-19 | — | — | CN | disclosed |
| CN-1774435-A | 5-membered heterocyclic derivative | DAIICHI SEIYAKU CO (JP) | 2006-05-17 | — | — | CN | disclosed |
| CN-1070480-C | 2-amino-benzoxanones for the treatment of viral infections | SEARLE & CO (US) | 2001-09-05 | — | — | CN | disclosed |
| CN-1230187-A | Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors | GLAXO GROUP LTD (GB) | 1999-09-29 | — | — | CN | disclosed |
| CN-1151396-A | Hydroxylamine derivatives and fungicides containing the same | NIHON NOHYAKU CO LTD (JP) | 1997-06-11 | — | — | CN | disclosed |
| CN-86107220-A | Δ 2-1, the preparation method and the application method thereof of 2,4 triazolines-5-ketone derivatives | — | 1987-09-30 | — | — | CN | disclosed |