SCHEMBL27363864

SCHEMBL27363864

c1ccc(-c2ccc3sc4c(-c5ccccc5)nc(-c5ccc(-n6c7ccccc7c7cc8ccccc8cc76)c6c5oc5ccccc56)nc4c3c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 3/20 0.33
PIM2 Q9P1W9 3/20 0.33
PIM3 Q86V86 2/20 0.33
LIMK1 P53667 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27363948 0.88 PIM1 (0.31) PIM1PIM2PIM3
SCHEMBL27364133 0.88 PIM1 (0.38) PIM1PIM2PIM3
SCHEMBL27363874 0.88 PIM1 (0.38) PIM1PIM2PIM3
SCHEMBL27367765 0.87
SCHEMBL21863164 0.87 PRKDC (0.31)
SCHEMBL27363866 0.86 PIM1 (0.35) PIM1PIM2PIM3LIMK1
SCHEMBL27363877 0.85 PIM1 (0.38) PIM1PIM2PIM3
SCHEMBL27363869 0.85 PIM1 (0.38) PIM1PIM2PIM3
SCHEMBL27364127 0.85 PIM1 (0.33) PIM1PIM2PIM3LIMK1
SCHEMBL21736636 0.84 PIM1 (0.34) PIM1PIM2PIM3LIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240215277-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2024-06-27 US disclosed
US-20240215277-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2024-06-27 US disclosed