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Sugi Predict / Compounds / SCHEMBL27363937

SCHEMBL27363937

SCHEMBL27363937

c1ccc(-c2ccc3oc4c(-c5ccc6c(c5)oc5ccccc56)nc(-c5ccc(-n6c7ccccc7c7cc8ccccc8cc76)c6oc7ccccc7c56)nc4c3c2)cc1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ PIM1 P11309 1/20 0.35
▸ CSNK2A2 P19784 1/20 0.35
▸ CSNK2B P67870 1/20 0.35
▸ PIM3 Q86V86 1/20 0.35
▸ PIM2 Q9P1W9 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.30
▸ HPGD P15428 1/20 0.30
▸ TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27363870 0.94 PIM1 (0.35) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27363944 0.94 PIM1 (0.37) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27363942 0.94 TSHR (0.33) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27363954 0.91 PIM1 (0.35) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27363943 0.91 PIM1 (0.35) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27363997 0.90 PIM1 (0.36) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27363964 0.90 PIM1 (0.37) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL27363947 0.89 PIM1 (0.30) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL23449722 0.88 PRKDC (0.32) —
SCHEMBL27364133 0.88 PIM1 (0.38) PIM1CSNK2A2CSNK2BPIM3PIM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240215277-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2024-06-27 — — US disclosed
US-20240215277-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2024-06-27 — — US disclosed