Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.69 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | APEX1 | P27695 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17562151 | 0.90 | KMT2A (0.71) | ATMKMT2AMEN1CYP1A2LMNA | |
| SCHEMBL11716945 | 0.90 | ATM (0.64) | ATMKMT2AMEN1CYP1A2LMNA | |
| SCHEMBL595243 | 0.88 | ATM (0.69) | ATMKMT2AMEN1CYP1A2LMNA | |
| SCHEMBL14090017 | 0.88 | ATM (0.61) | ATMKMT2AMEN1CYP1A2LMNA | |
| SCHEMBL14090016 | 0.88 | ATM (0.61) | ATMKMT2AMEN1CYP1A2LMNA | |
| SCHEMBL21287022 | 0.86 | ATM (0.59) | ATMKMT2AMEN1CYP1A2LMNA | |
| SCHEMBL21861467 | 0.85 | ATM (0.58) | ATMKMT2AMEN1CYP1A2LMNA | |
| SCHEMBL21675546 | 0.85 | KMT2A (0.64) | ATMKMT2AMEN1CYP1A2LMNA | |
| SCHEMBL2736392 | 0.85 | ATM (0.66) | ATMKMT2AMEN1CYP1A2LMNA | |
| SCHEMBL30494683 | 0.84 | KMT2A (0.97) | ATMKMT2AMEN1CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8766242-B2 | Aromatic chalcogen compounds and their use | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-07-01 | — | — | US | disclosed |
| US-20120068166-A1 | AROMATIC CHALCOGEN COMPOUNDS AND THEIR USE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-22 | — | — | US | disclosed |
| US-8089064-B2 | Aromatic chalcogen compounds and their use | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-03 | — | — | US | disclosed |
| US-20090121627-A1 | AROMATIC CHALCOGEN COMPOUNDS AND THEIR USE | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-05-14 | — | — | US | disclosed |
| US-7504769-B2 | Aromatic chalcogen compounds and their use | E. I. DU PONT DE NEMOURS + COMPANY (US) | 2009-03-17 | — | — | US | disclosed |