Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCS1 | P62166 | 1/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.57 |
| ▸ | CSNK1D | P48730 | 11/20 | 0.57 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.56 |
| ▸ | FES | P07332 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | CDK2 | P24941 | 1/20 | 0.56 |
| ▸ | GSK3A | P49840 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.56 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.56 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.56 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.56 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.56 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.56 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.56 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17770327 | 0.88 | KDM4E (0.69) | NCS1DYRK1ACSNK1DDCLK1FES | |
| SCHEMBL19612139 | 0.87 | DYRK1A (0.60) | NCS1DYRK1ACSNK1DACP1CYP2D6 | |
| SCHEMBL19612144 | 0.87 | DYRK1A (0.60) | DYRK1ACSNK1DACP1CYP2D6LRRK2 | |
| SCHEMBL19612167 | 0.85 | DYRK1A (0.58) | NCS1DYRK1ACSNK1DACP1CYP2D6 | |
| SCHEMBL19612122 | 0.85 | DYRK1A (0.57) | NCS1DYRK1ACSNK1DDCLK1FES | |
| SCHEMBL19612097 | 0.85 | DYRK1A (0.57) | NCS1DYRK1ACSNK1DACP1CYP2D6 | |
| SCHEMBL30810362 | 0.84 | DYRK1A (0.56) | NCS1DYRK1ACSNK1DACP1CYP2D6 | |
| SCHEMBL27364347 | 0.84 | CSNK1D (0.54) | NCS1DYRK1ACSNK1DACP1CYP2D6 | |
| SCHEMBL19612088 | 0.83 | CSNK1D (0.58) | DYRK1ACSNK1DACP1CYP2D6LRRK2 | |
| SCHEMBL19612100 | 0.83 | CSNK1D (0.51) | NCS1DYRK1ACSNK1DACP1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054766-A2 | MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | MITO BIOPHARMA, LLC (US) | 2024-03-14 | — | — | WO | disclosed |