Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.63 |
| ▸ | CNR1 | P21554 | 6/20 | 0.63 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.53 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | CDK9 | P50750 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27311977 | 0.95 | SRD5A1 (0.64) | CNR2CNR1SRD5A1SRD5A2KMT2A | |
| SCHEMBL16201688 | 0.85 | CNR2 (0.80) | CNR2CNR1 | |
| SCHEMBL8791719 | 0.84 | SRD5A1 (0.62) | CNR2CNR1SRD5A1SRD5A2KMT2A | |
| SCHEMBL8792188 | 0.82 | SRD5A1 (0.63) | CNR2CNR1SRD5A1SRD5A2KMT2A | |
| SCHEMBL9390912 | 0.82 | CNR1 (0.56) | CNR2CNR1SRD5A1SRD5A2KMT2A | |
| SCHEMBL11903696 | 0.81 | CNR2 (0.74) | CNR2CNR1 | |
| SCHEMBL8792359 | 0.81 | SRD5A1 (0.58) | CNR2CNR1SRD5A1SRD5A2KMT2A | |
| SCHEMBL8959936 | 0.80 | CREBBP (0.60) | CNR2CNR1SRD5A1SRD5A2KMT2A | |
| SCHEMBL11154740 | 0.80 | CNR2 (0.67) | CNR2CNR1KMT2A | |
| SCHEMBL7853735 | 0.80 | CNR1 (0.70) | CNR2CNR1SRD5A1SRD5A2CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1067985-C | Indole derivative and medicine containing the same | ZERIA PHARM CO LTD (JP) | 2001-07-04 | — | — | CN | disclosed |
| CN-1145617-A | Indole derivatives and drugs containing the same | ZERIA PHARM CO LTD (JP) | 1997-03-19 | — | — | CN | disclosed |