SCHEMBL27365083

SCHEMBL27365083

CNC(C)CC(C)(NC)NC

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.30
SLC18A2 Q05940 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17282077 0.77
SCHEMBL2691976 0.77
SCHEMBL11856883 0.77
SCHEMBL10273870 0.74
SCHEMBL28912944 0.72
SCHEMBL12463255 0.72
SCHEMBL20282161 0.72 TAAR1 (0.30) TAAR1SLC18A2SIGMAR1
SCHEMBL31345059 0.72
SCHEMBL24163105 0.70
SCHEMBL19116426 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101287712-B Heterocyclic compounds S BIO PTE LTD 2012-10-31 CN claimed
CN-101218238-B Imidazo[1,2-a]pyridine derivatives: preparation and pharmaceutical applications S BIO PTE LTD 2011-10-26 CN claimed
CN-101287712-A Heterocyclic compounds S BIO PTE LTD (SG) 2008-10-15 CN claimed
CN-101218238-A Imidazo[1,2-a]pyridine derivatives: preparation and pharmaceutical applications S BIO PTE LTD (SG) 2008-07-09 CN claimed
CN-1902294-A Aromatic Hydrocarbon-Containing Heat Transfer Fluids for Cryogenic Applications SOLUTIA EUROP NV SA (BE) 2007-01-24 CN claimed
CN-1280300-C Heterocyclic metallocene compounds and use thereof in catalyst systems for producing olefin polymers BASELL TECHNOLOGY CO BV (NL) 2006-10-18 CN claimed
CN-1161388-C Metallocene compounds, process for their preparation and their use in catalytic systems for polymerization of olefins 2004-08-11 CN claimed
CN-1140538-C Pre-polymerized catalyst components for the polymerization of olefins ض� 2004-03-03 CN claimed
CN-1348459-A Heterocyclic metallocene compounds and their use in catalyst systems for producing olefin polymers BASELL TECHNOLOGY CO BV (NL) 2002-05-08 CN claimed
CN-1068895-C Flame-resistant polycarbonate moulding compositions BAYER AG (DE) 2001-07-25 CN claimed
CN-1293677-A Preparation of bridged metallocenes and use in catalytic systems MONTELL TECHNOLOGY COMPANY BV (NL) 2001-05-02 CN claimed
CN-1293667-A Gas phase process for epoxidation of non-allylic alkenes EASTMAN CHEM CO (US) 2001-05-02 CN claimed
CN-1287560-A Pre-polymerized catalyst components for the polymerization of olefins MONTELL TECHNOLOGY COMPANY BV (NL) 2001-03-14 CN claimed
CN-1277618-A Process for the preparation of substantially amorphous alpha-olefin polymers, compositions containing them and process for the preparation of bridged ligand MONTELL TECHNOLOGY COMPANY BV (NL) 2000-12-20 CN claimed
CN-1128277-A Flame-resistant polycarbonate moulding compositions BAYER AG (DE) 1996-08-07 CN claimed
CN-1102825-A Functionalized photoinitiators, macromers thereof, and the use thereof CIBA GEIGY AG (CH) 1995-05-24 CN claimed
CN-104185645-A Process for producing nitrile rubber in organic solvent LANXESS DEUTSCHLAND GMBH 2014-12-03 CN disclosed
CN-102282182-B Polyethylene copolymers BASELL POLYOLEFINE GMBH 2014-11-12 CN disclosed
CN-1128277-A Flame-resistant polycarbonate moulding compositions BAYER AG (DE) 1996-08-07 CN disclosed
CN-1102825-A Functionalized photoinitiators, macromers thereof, and the use thereof CIBA GEIGY AG (CH) 1995-05-24 CN disclosed